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Key findings included: Excellent tolerability with less than 10% reporting any digestive discomfort Dose-dependent biological responses indicating successful butyrate generation Favorable shifts in markers such as hs-CRP Metabolic effects suggesting enhanced butyrate availability Confirmation that 200mg daily appears to be the optimal dose The ButyraGen Clinical Breakthrough (Dosz 2025) The second study focused on individuals seeking digestive comfort, providing even more compelling results

Patients were excluded if they had an opioid-involved overdose in the 9 months prior to study entry